Let's Hear It For The Poo!
Nov. 6th, 2013 06:37 pmMany, many years ago I noted that the hyper-sanitary paradigm of health, the mantra that Cleaner is Always Better, might be making us sicker. Specifically, researchers have been doing things that totally trigger the Icky! factor in us, notably administering feces to patients as a cure for their conditions.
I first heard about this on the Scientific American podcast Science Talk, which now seems to be transcripted. As journalist Mary McKenna explained back then on the topic of poop chute infusions to combat C diff:
Well, that paradigm is happily changing, and fast!
No more bowing to the Icky! Observation has trumped!
I first heard about this on the Scientific American podcast Science Talk, which now seems to be transcripted. As journalist Mary McKenna explained back then on the topic of poop chute infusions to combat C diff:
It's better than any drug we have. And yet what's so interesting about it is that it works, just unquestionably works in a clinical sense—there is case series after case series that now shows this; a couple of dozen case series—but it doesn't work in a regulatory sense. It hasn't been approved by the FDA and because it hasn't been approved by the FDA, NIH can't figure out a way to fund further research, because feces are not any of the things that the FDA licenses. They're not a device, they're not a drug, they're not what we call a tissue, really—they're not something like a replacement joint or replacement tendon or the replacement lens of an eye. So they're caught in this kind of regulatory no man's land.
Well, that paradigm is happily changing, and fast!
SEATTLE — Conventional wisdom says it takes 15 years for a medical therapy, once proven safe and effective, to be widely accepted by the medical profession.
In the case of one particular treatment, however, a growing cadre of doctors and patients turned conventional wisdom on its head, enthusiastically adopting a procedure before the evidence was in — so enthusiastically, in fact, that the Food and Drug Administration was recently forced to rescind its restrictions.
The treatment, now widely employed against recurrent attacks by a nasty intestinal bug known as Clostridium difficile and tested on Crohn’s disease and colitis, is one you’ll likely never see advertised on TV: the fecal microbiota transplant, politely known as the FMT.
No more bowing to the Icky! Observation has trumped!